{"created":"2023-07-27T11:42:50.882432+00:00","id":75704,"links":{},"metadata":{"_buckets":{"deposit":"32fad56c-2970-4533-8664-a9dbc605547c"},"_deposit":{"created_by":10,"id":"75704","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"75704"},"status":"published"},"_oai":{"id":"oai:gifu-u.repo.nii.ac.jp:00075704","sets":["2060:2090:2091"]},"author_link":["415483","415484","415482"],"item_3_alternative_title_23":{"attribute_name":"タイトル（ヨミ）","attribute_value_mlt":[{"subitem_alternative_title":"ケイショキハイ ノ ムカク バイヨウケイ オ モチイタ ショク ノ アンゼンセイ キノウセイ ノ シンヒョウカ システム ノ カイハツ","subitem_alternative_title_language":"ja-Kana"}]},"item_3_biblio_info_6":{"attribute_name":"雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006-03","bibliographicIssueDateType":"Issued"}}]},"item_3_description_35":{"attribute_name":"目次","attribute_value_mlt":[{"subitem_description":"14-21p: Ichihara A. et al., Inhibition of Diabetic Nephropathy by a Decoy Peptide Corresponding to the \"Handle\" Region for Nonproteolytic Activation of Prorenin. Journal of Clinical Investigation. 2004 114(8): 1128-1135","subitem_description_language":"en","subitem_description_type":"TableOfContents"},{"subitem_description":"22-28p: Kawazu S. et al., Sex Difference and Possible Relationship to Microvascular Complications of Serum Prorenin Levels in Type 2 Diabetic Patients, Measured by a Novel Antibody-Activating Direct Enzyme Kinetic Assay. Journal of Diabetes and Its Complications. 2004 18(5): 275-281","subitem_description_language":"en","subitem_description_type":"TableOfContents"},{"subitem_description":"29-31p: Yokota H. et al., Serum Prorenin Levels and Diabetic Retinopathy in Type 2 Diabetes: New Method to Measure Serum Level of Prorenin Using Antibody Activating Direct Kinetic Assay. British Journal of Ophthalmology. 2005 89(7): 871-873","subitem_description_language":"en","subitem_description_type":"TableOfContents"},{"subitem_description":"32-36p: Nabi A. H. M. N. et al., Roles of His9 (P2 Subsite) and His13 (P3' Subsite) in Angiotensinogen for Catalytic Reaction of Renin. International Journal of Molecular Medicine. 2005 16(1): 103-107","subitem_description_language":"en","subitem_description_type":"TableOfContents"},{"subitem_description":"37-42p: Satou R. et al., Angiotensin II and III Upregulate Body Fluid Volume of the Clam Worm Perinereis sp. via Angiotensin II Receptors in Different Manners. Peptides. 2005 26(12): 2452-2457","subitem_description_language":"en","subitem_description_type":"TableOfContents"},{"subitem_description":"43-47p: Satou R. et al., Angiotensin III As Well As Angiotensin II Regulates Water Flow through Aquaporins in a Clam Worm. Bioscience, Biotechnology, and Biochemistry. 2005 69(7): 1221-1225","subitem_description_language":"en","subitem_description_type":"TableOfContents"},{"subitem_description":"48-52p: Nasir U. M. et al., Laughter therapy Modulates the Parameters of Renin-Angiotensin System in Patients with Type 2 Diabetes. International Journal of Molecular Medicine. 2005 16(6): 1077-1081","subitem_description_language":"en","subitem_description_type":"TableOfContents"}]},"item_3_description_46":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"研究報告書","subitem_description_type":"Other"}]},"item_3_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"平成16年度-平成17年度年度科学研究費補助金 (基盤研究(C)　一般 食の安全　課題番号16613002) 研究成果報告書","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"本年度においては、まず1)ニワトリ受精卵の無殻培養(シャーレ内)系の胚発生過程における胚、卵黄血管系、尿漿膜血管系、網細血管(血管新生)等を肉眼および実体顕微鏡を通した静止及び動画として経時的に記録し、上記測定対象の変化量を画像処理で数量化するシステムを構築した。併せて、観察面のみを除去した有殻培養系での胚発生過程における上記パラメータの数量化システムも構築し、無殻培養系システムと比較した。具体的には、上記2つの培養系において、すでに確立した方法を用いて、血管系の肉眼方向からの投射面積の数量化を試みた。「肉眼レベル」および「実体顕微鏡レベル」において撮影した画像を市販の画像処理ソフトウエアで対象部分のみを切り出し、該当部分の面積は、面積既知部分を対照として市販の面積解析ソフトで求めた。その結果、無殻培養系システムの方が安定し胚発生が観察でき、血管系の観察を可能にした。また、血管新生の引き金になるレニン・アンジオテンシン系の生化学的動態の測定法とデータのパラメータ化についても検討した。特に各パラメータのmRNAのRT-PCR法による定量法確立のための予備実験を行った。以上、次年度における「食の安全性評価システム」としての評価モデル実験に備えることができた。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_3_full_name_2":{"attribute_name":"著者(ヨミ)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"415483","nameIdentifierScheme":"WEKO"}],"names":[{"name":"スズキ, フミアキ","nameLang":"ja-Kana"}]}]},"item_3_full_name_3":{"attribute_name":"別言語の著者","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"415484","nameIdentifierScheme":"WEKO"}],"names":[{"name":"SUZUKI, Fumiaki","nameLang":"en"}]}]},"item_3_text_47":{"attribute_name":"資源タイプ・ローカル","attribute_value_mlt":[{"subitem_text_value":"研究報告書"}]},"item_3_text_48":{"attribute_name":"資源タイプ・NII","attribute_value_mlt":[{"subitem_text_value":"Research Paper"}]},"item_3_text_49":{"attribute_name":"資源タイプ・DCMI","attribute_value_mlt":[{"subitem_text_value":"text"}]},"item_3_text_50":{"attribute_name":"資源タイプ・ローカル表示コード","attribute_value_mlt":[{"subitem_text_value":"04"}]},"item_3_text_80":{"attribute_name":"科研費番号","attribute_value_mlt":[{"subitem_text_value":"16613002"}]},"item_3_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"鈴木, 文昭","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"415482","nameIdentifierScheme":"WEKO"}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ニワトリ","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"初期胚","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"食の安全","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"機能評価","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"鶏初期胚の無殻培養系を用いた食の安全性・機能性の新評価システムの開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"鶏初期胚の無殻培養系を用いた食の安全性・機能性の新評価システムの開発","subitem_title_language":"ja"}]},"item_type_id":"3","owner":"10","path":["2091"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2008-03-12"},"publish_date":"2008-03-12","publish_status":"0","recid":"75704","relation_version_is_last":true,"title":["鶏初期胚の無殻培養系を用いた食の安全性・機能性の新評価システムの開発"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2024-02-05T05:08:51.086095+00:00"}